Increased rate of hip fractures with certain medications

Proton Pump Inhibitor (ie. Prilosec, Prevacid), corticosteroids (ie. Prednisone), SSRI antidepressants (ie. Prozac, Wellbutrin, Zoloft ) and osteoporosis drugs (Boniva, Fosamax).  That is right.  Drugs given to prevent hip fractures are on the list.  Taking these medications increase the risk of spontaneous (while walking, without falling or trauma) fracture at the neck of the leg bone (femur).

Here’s why:

Ant-acids such as Prilosec and Prevacid reduce the acid in your stomach.   Calcium needs an acidic stomach to be absorbed.  The less acidic stomach absorbs less calcium.

Steroids like Prednisone slow your body’s healing processes including rebuilding and remolding bone.  Rebuilding and remodeling bone is an on going process.  Corticosteroids significantly slow rebuilding and remodeling.

Anti-depressant use increases hip fractures but the reason is not yet understood.

Osteoporosis drugs, such as Boniva, Fosamax and Reclast prevent the rebuilding and remodeling of bone which results in thicker but more brittle bones.

Dr. Shoemaker says healthy bone mass requires weight bearing exercise such as walking, vitamin D3 and high quality calcium supplements such as MCHC calcium or calcium citrate.


  1. Nice article. Keep up the good work of informing us on ways to keep good health and strong bodies.

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